Product Name: SWAP70 (D5O6A) Rabbit mAb#33942
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 478-08-0
Product: Lucidin
Specificity Sensitivity: SWAP70 (D5O6A) Rabbit mAb recognizes endogenous levels of total SWAP70 protein.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp536 of human SWAP70 protein.
Background: SWAP70 is a Rac family guanine nucleotide exchange factor (GEF) (1). It is highly expressed by activated B cells. Following B cell stimulation, SWAP70 has been observed to translocate from the cytoplasm to the nucleus, where it plays a role in class switc
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22084434?dopt=Abstract
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