Product Name: SOS1 (D3T7T) Rabbit mAb#12409
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 423148-78-1
Product: PYZD-4409
Specificity Sensitivity: SOS1 (D3T7T) Rabbit mAb recognizes endogenous levels of total SOS1 protein.
Species Reactivity: Human, Mouse, Rat, Hamster, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro1250 of human SOS1 protein.
Background: Son of sevenless (SOS) was first identified in Drosophila as a guanine nucleotide exchange factor (GEF) for Ras acting downstream of the Sevenless receptor (1). Two closely related homologs of Drosophila SOS are found in mammalian cells: SOS1 and SOS2 (2)
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19667074?dopt=Abstract
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