Product Name: SMG-1 (Q25) Antibody#4993
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 664993-53-7
Product: JW 55
Specificity Sensitivity: SMG-1 (Q25) Antibody recognizes endogenous levels of total SMG-1/ATX protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to amino terminal residues of human SMG-1. Antibodies are purifed using protein A and peptide affinity chromatography.
Background: SMG-1 is a member of the phosphoinositide 3-kinase-related kinase (PIKK) family, which includes ATM, ATR, mTOR, DNA-PKcs, and TRRAP (1,2). Activated by DNA damage, SMG-1 has been shown to phosphorylate p53 and hUpf1 (SMG-2) (1-4). hUpf1 is a subunit of th
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23307829?dopt=Abstract
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