Product Name: SHMT1 (D3B3J) Rabbit mAb#80715
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 869185-85-3
Product: SB 203580 (hydrochloride)
Specificity Sensitivity: SHMT1 (D3B3J) recognizes endogenous levels of total SHMT1 protein. This antibody does not cross-react with SHMT2 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Glu187 of human SHMT1 protein.
Background: Serine hydroxymethyltransferases 1 and 2 (SHMT1, SHMT2) are cytoplasmic and mitochondrial serine hydroxylmethyltransferases, respectively (1,2). They catalyze the conversion of serine to glycine with the transfer of β-carbon from serine to tetrahydrofolat
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24795345?dopt=Abstract
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