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Product Name: SEK1/MKK4 Antibody#9152
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1169562-71-3
Product: XL413 (hydrochloride)
Specificity Sensitivity: SEK1/MKK4 Antibody detects endogenous levels of total SEK1/MKK4 protein. This antibody does not cross-react with MEK1, MEK2 or MKK3.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding the N-terminus of human SEK1/MKK4. Antibodies are purified by protein A and peptide affinity chromatography.
Background: SAPK/Erk kinase (SEK1), also known as MKK4 or Jun kinase kinase (JNKK), activates the MAP kinase homologues SAPK and JNK in response to various cellular stresses and inflammatory cytokines (1-3). Activation of SEK1 occurs through MEKK phosphorylation of s
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22796220?dopt=Abstract

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Author: Interleukin Related