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Product Name: SAMHD1 Antibody#12361
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 169274-78-6
Product: Ro 25-6981
Specificity Sensitivity: SAMHD1 Antibody recognizes endogenous levels of total SAMHD1 protein. This antibody cross-reacts with a 30 kDa protein of unknown origin.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro607 of human SAMHD1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: SAM domain and HD domain-containing protein 1 (SAMHD1) is a negative regulator of the cell-intrinsic innate immune response (1). Research studies have identified mutations in SAMHD1 as a cause of Aicardi-Goutieres syndrome, an autoimmune disease character
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18337230?dopt=Abstract

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Author: Interleukin Related