Product Name: RyR1 (D4E1) Rabbit mAb#8153
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 24219-97-4
Product: Mianserin
Specificity Sensitivity: RyR1 (D4E1) Rabbit mAb recognizes endogenous levels of total RyR1 protein. This antibody does not cross-react with other ryanodine receptor proteins.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg830 of human RyR1 protein.
Background: Ryanodine receptors (RyRs) are large (>500 kDa), intracellular calcium channels found in the sarcoplasmic/endoplasmic reticulum membrane and are responsible for the release of Ca2+ from intracellular stores in excitable cells, such as muscle and neuron
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23966837?dopt=Abstract
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