Product Name: Ras-GRF1 Antibody#3322
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1238673-32-9
Product: UNC0321
Specificity Sensitivity: Ras-GRF1 Antibody detects transfected levels of Ras-GRF1. This antibody does not cross-react with Ras-GRF2.
Species Reactivity: Mouse
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the amino-terminal residues of mouse Ras-GRF1. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Ras activity is regulated by GAP (GTPase activating proteins) and GEFs (guanine nucleotide exchange factors). Ras-GRF1 (also known as CDC25Mm) is neuronal RasGEF and is regulated by heterotrimeric G proteins and calcium influx (1,2). Binding to calmodulin
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22538615?dopt=Abstract
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