Product Name: Rab4 Antibody#2167
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 749886-87-1
Product: JSH-23
Specificity Sensitivity: Rab4 Antibody detects endogenous levels of total Rab4 protein.
Species Reactivity: Human, Mouse, Rat, Hamster, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp128 of human Rab4 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Rab4 is a member of the Ras superfamily of small Rab GTPases implicated in endocytosis. Rab4 is localized at early endosomes/recycling endosomes and functions as a key regulator for sorting/recycling of membrane and proteins (1,2). Rab4 has two isoforms,
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20403362?dopt=Abstract
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