Product Name: Rab27A (D7Z9Q) Rabbit mAb#69295
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 97759-16-5
Product: S186
Specificity Sensitivity: Rab27A (D7Z9Q) Rabbit mAb recognizes endogenous levels of total Rab27a protein.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human Rab27a protein.
Background: Rab27 is a member of the Ras superfamily of small Rab GTPases implicated in exocytosis (1-2). The protein is localized in secretory lysosomes, such as melanosomes in melanocyte or lytic granules in cytotoxic T cells to control exosome secretion pathway (3
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25082960?dopt=Abstract
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