Product Name: RIP (D94C12) XP® Rabbit mAb#3493
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 434-13-9
Product: Lithocholic acid
Specificity Sensitivity: RIP (D94C12) XP® Rabbit mAb detects endogenous levels of total RIP (RIP1) protein. It has not been shown to cross-react with other RIP family members.
Species Reactivity: Human, Mouse, Rat, Hamster, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu190 of human RIP.
Background: The receptor-interacting protein (RIP) family of serine-threonine kinases (RIP, RIP2, RIP3, and RIP4) are important regulators of cellular stress that trigger pro-survival and inflammatory responses through the activation of NF-κB, as well as pro-apoptoti
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20584904?dopt=Abstract
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