Product Name: RAD21 (L611) Antibody#4449
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:25
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1374639-75-4
Product: LEE011 (succinate)
Specificity Sensitivity: RAD21 (L611) Antibody detects endogenous levels of total RAD21 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the carboxy terminus of the human RAD21 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: The cohesin complex consists of a heterodimer between SMC1 (SMC1A or B) and SMC3, bound by additional RAD21 and STAG proteins (STAG1, 2, or 3) (1,2). These proteins form a ring-like structure that mediates the cohesion of two sister chromatids after DNA r
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22359590?dopt=Abstract
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