Product Name: Prostate Specific Membrane Antigen (D4S1F) Rabbit mAb#12702
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 451492-95-8
Product: AV-412 (free base)
Specificity Sensitivity: Prostate Specific Membrane Antigen (D4S1F) Rabbit mAb recognizes endogenous levels of total prostate specific membrane antigen. An SDS resistant dimer at approximately 200 kDa can be detected depending on sample preparation conditions.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues in the extracellular domain of human prostate specific membrane antigen protein.
Background: Prostate specific membrane antigen (PSMA, also known as FOLH1), a type II transmembrane protein of the M28 family, has both folate hydrolase and N-acetylated-alpha-linked acidic dipeptidase activity. PSMA was originally identified in the LNCaP cell line,
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21844185?dopt=Abstract
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