Product Name: Phospho-Talin (Ser425) (D2P2M) Rabbit mAb#13589
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 55721-31-8
Product: Salinomycin (sodium salt)
Specificity Sensitivity: Phospho-Talin (Ser425) (D2P2M) Rabbit mAb recognizes endogenous levels of talin protein only when phosphorylated at Ser425. Based on sequence homology, this antibody is expected to recognize both talin-1 and talin-2 proteins phosphorylated at Ser425.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser425 of human talin protein.
Background: Focal adhesions connect the cytoskeleton with the extracellular matrix (ECM), a complex structure of secreted macromolecules that surrounds mammalian organs and tissues. Integrins clustered on the extracellular side of focal adhesions signal from the ECM
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19074834?dopt=Abstract
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