Product Name: Phospho-TAK1 (Thr187) Antibody#4536
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 154-42-7
Product: 6-Thioguanine
Specificity Sensitivity: Phospho-TAK1 (Thr187) Antibody detects endogenous levels of TAK1 only when phosphorylated at threonine 187.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr187 of human TAK1. Antibodies are purified by protein A and affinity chromatography.
Background: TAK1 is a mitogen-activated protein kinase kinase kinase that can be activated by TGF-β, bone morphogenetic protein and other cytokines including IL-1 (1,2). In vivo activation of TAK1 requires association with TAK1 binding protein 1 (TAB1), which trigger
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21402791?dopt=Abstract
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