Product Name: Phospho-TAK1 (Thr184) Antibody#4537
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 50-44-2
Product: 6-Mercaptopurine
Specificity Sensitivity: Phospho-TAK 1(Thr184) Antibody detects endogenous levels of TAK1 only when phosphorylated at threonine 184.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a phosphopeptide corresponding to residues surrounding Thr184 of human TAK1. Antibodies are purified by protein A and affinity chromatography.
Background: TAK1 is a mitogen-activated protein kinase kinase kinase that can be activated by TGF-β, bone morphogenetic protein and other cytokines including IL-1 (1,2). In vivo activation of TAK1 requires association with TAK1 binding protein 1 (TAB1), which trigger
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23838596?dopt=Abstract
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