Product Name: Phospho-Survivin (Thr34) (D2E11) Rabbit mAb#8888
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 111406-87-2
Product: Zileuton
Specificity Sensitivity: Phospho-Survivin (Thr34) (D2E11) Rabbit mAb recognizes endogenous levels of survivin protein only when phosphorylated at Thr34.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Thr34 of human survivin protein.
Background: Survivin is a 16 kDa anti-apoptotic protein highly expressed during fetal development and cancer cell malignancy (1). Survivin binds and inhibits caspase-3, controlling the checkpoint in the G2/M-phase of the cell cycle by inhibiting apoptosis and promoti
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23318430?dopt=Abstract
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