Product Name: Phospho-Stat3 (Tyr705) (3E2) Mouse mAb#9138
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 945755-56-6
Product: XL019
Specificity Sensitivity: Phospho-Stat3 (Tyr705) (3E2) Mouse mAb detects endogenous levels of Stat3 only when phosphorylated at tyrosine 705. The antibody does not significantly cross-react with other members of the Stat family.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr705 of mouse Stat3.
Background: The Stat3 transcription factor is an important signaling molecule for many cytokines and growth factor receptors (1) and is required for murine fetal development (2). Research studies have shown that Stat3 is constitutively activated in a number of human
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18571648?dopt=Abstract
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