Product Name: Phospho-Smad2 (Ser245/250/255) Antibody#3104
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 56390-09-1
Product: Epirubicin (hydrochloride)
Specificity Sensitivity: Phospho-Smad2 (Ser245/250/255) Antibody detects endogenous levels of Smad2 only when phosphorylated at serines 245, 250 or 255.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding serines 245/250/255 of Smad2. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Members of the Smad family of signal transduction molecules are components of a critical intracellular pathway that transmit TGF-β signals from the cell surface into the nucleus. Three distinct classes of Smads have been defined: the receptor-regulated Sm
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19574298?dopt=Abstract
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