Product Name: Phospho-Smad1/5 (Ser463/465) (41D10) Rabbit mAb#9516
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1176316-99-6
Product: Agomelatine (hydrochloride)
Specificity Sensitivity: Phospho-Smad1/5 (Ser463/465) (41D10) Rabbit mAb detects endogenous levels of Smad1 and Smad5 only when dually phosphorylated at Ser463 and Ser465 and is also predicted to detect Smad9 (Smad8) when phosphorylated at Ser465 and Ser467. The antibody does not
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser463/465 of human Smad5.
Background: Bone morphogenetic proteins (BMPs) constitute a large family of signaling molecules that regulate a wide range of critical processes including morphogenesis, cell-fate determination, proliferation, differentiation, and apoptosis (1,2). BMP receptors are m
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21402790?dopt=Abstract
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