Product Name: Phospho-SMC1 (Ser360) Antibody#4029
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 124937-51-5
Product: Tolterodine
Specificity Sensitivity: Phospho-SMC1 (Ser360) Antibody detects endogenous levels of SMC1 protein only when phosphorylated on Ser360. This antibody does not cross-react with other SMC proteins.
Species Reactivity: Human, Mouse, Rat
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to Ser360 of the human SMC1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair (1,2). ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser9
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17998396?dopt=Abstract
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