Product Name: Phospho-SLP-76 (Tyr145) Antibody#14770
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 56180-94-0
Product: Acarbose
Specificity Sensitivity: Phospho-SLP-76 (Tyr145) Antibody recognizes endogenous levels of SLP-76 protein only when phosphorylated at Tyr145. The antibody may cross-react with phospho-BLNK in B cells.
Species Reactivity: Human, Mouse
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr145 of human SLP-76 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: SH2 domain-containing leukocyte protein of 76 kDa (SLP-76) is a hematopoietic adapter protein that is important in multiple biochemical signaling pathways and necessary for T cell development and activation (1). ZAP-70 phosphorylates SLP-76 and LAT as a r
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24757167?dopt=Abstract
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