Product Name: Phospho-SHP-2 (Tyr580) (D66F10) Rabbit mAb#5431
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:200
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 206184-49-8
Product: Tenofovir (hydrate)
Specificity Sensitivity: Phospho-SHP-2 (Tyr580) (D66F10) Rabbit mAb detects endogenous level of SHP2 only when phosphorylated at Tyr580.
Species Reactivity: Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr580 of human SHP2 protein.
Background: SHP-2 (PTPN11) is a ubiquitously expressed, nonreceptor protein tyrosine phosphatase (PTP). It participates in signaling events downstream of receptors for growth factors, cytokines, hormones, antigens, and extracellular matrices in the control of cell gr
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23328673?dopt=Abstract
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