Product Name: Phospho-SHP-2 (Tyr542) Antibody#3751
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 220620-09-7
Product: Tigecycline
Specificity Sensitivity: Phospho-SHP-2 (Tyr542) Antibody detects endogenous levels of SHP-2 only when phosphorylated at Tyr542. This antibody may cross-react with activated receptor tyrosine kinases.
Species Reactivity: Human, Mouse, Rat
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr542 of human SHP-2 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: SHP-2 (PTPN11) is a ubiquitously expressed, nonreceptor protein tyrosine phosphatase (PTP). It participates in signaling events downstream of receptors for growth factors, cytokines, hormones, antigens, and extracellular matrices in the control of cell gr
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23539757?dopt=Abstract
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