Product Name: Phospho-SHIP2 (Tyr1135) (D33C6) XP® Rabbit mAb#5445
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:200
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 103628-48-4
Product: Sumatriptan (succinate)
Specificity Sensitivity: Phospho-SHIP2 (Tyr1135) (D33C6) XP® Rabbit mAb detects endogenous levels of SHIP2 protein only when phosphorylated at Tyr1135.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1135 of human SHIP2 protein.
Background: SH2-containing inositol phosphatase 1 (SHIP1) is a hematopoietic phosphatase that hydrolyzes phosphatidylinositol-3,4,5-triphosphate to phosphatidylinositol-3,4-bisphosphate (1). SHIP1 is a cytosolic phosphatase with an SH2 domain in its amino terminus an
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24282277?dopt=Abstract
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