Product Name: Phospho-SF3B1 (Thr313) (D8D8V) Rabbit mAb#25009
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 16994-56-2
Product: Reserpine (hydrochloride)
Specificity Sensitivity: Phospho-SF3B1 (Thr313) (D8D8V) Rabbit mAb recognizes endogenous levels of SF3B1 protein only when phosphorylated at Thr313.
Species Reactivity: Human, Mouse
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Thr313 of human SF3B1 protein.
Background: Splicing factor 3b subunit 1 (SF3B1) is an integral component of the U2 small nuclear ribonucleoprotein (U2 snRNP) and plays an important role in the splicing of pre-mRNA that involves the removal of introns and the joining of exons to form mature mRNA (1
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17307155?dopt=Abstract
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