Product Name: Phospho-SEK1/MKK4 (Ser257) (C36C11) Rabbit mAb#4514
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 681006-28-0
Product: AICAR (phosphate)
Specificity Sensitivity: Phospho-SEK1/MKK4 (Ser257) (C36C11) Rabbit mAb detects endogenous levels of SEK1/MKK4 phosphorylated at Ser257 .
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser257/Thr261 of human SEK1/MKK4.
Background: SAPK/Erk kinase (SEK1), also known as MKK4 or Jun kinase kinase (JNKK), activates the MAP kinase homologues SAPK and JNK in response to various cellular stresses and inflammatory cytokines (1-3). Activation of SEK1 occurs through MEKK phosphorylation of s
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25046804?dopt=Abstract
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