Product Name: Phospho-Rpb1 CTD (Ser2/Ser5) (D1G3K) Rabbit mAb#13546
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1369773-39-6
Product: AHU-377 (hemicalcium salt)
Specificity Sensitivity: Phospho-Rpb1 CTD (Ser2/Ser5) (D1G3K) Rabbit mAb recognizes endogenous levels of Rpb1 only when the carboxy-terminal domain (CTD) heptapeptide repeat [Tyr1, Ser2, Pro3, Thr4, Ser5, Pro6, Ser7] is dually phosphorylated at Ser2 and Ser5. This antibody does n
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser2/Ser5 of the human Rpb1 CTD heptapeptide repeat.
Background: RNA polymerase II (RNAPII) is a large multi-protein complex that functions as a DNA-dependent RNA polymerase, catalyzing the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1). The largest subunit, RNAPII subunit B
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26657744?dopt=Abstract
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