Product Name: Phospho-Rb (Ser807/811) (D20B12) XP® Rabbit mAb#8516
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:200
Immunohistochemistry: 1:400
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 28319-77-9
Product: sn-Glycero-3-phosphocholine
Specificity Sensitivity: Phospho-Rb (Ser807/811) (D20B12) XP® Rabbit mAb recognizes endogenous levels of Rb protein only when phosphorylated at Ser807, Ser811, or at both sites. This antibody does not cross-react with Rb phosphorylated at Ser608.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser807/811 of human Rb protein.
Background: The retinoblastoma tumor suppressor protein Rb regulates cell proliferation by controlling progression through the restriction point within the G1-phase of the cell cycle (1). Rb has three functionally distinct binding domains and interacts with critical
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19564415?dopt=Abstract
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