Product Name: Phospho-Rb (Ser608) (D10F2) Rabbit mAb#8147
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1197196-48-7
Product: UNC0224
Specificity Sensitivity: Phospho-Rb (Ser608) (D10F2) Rabbit mAb recognizes endogenous levels of Rb protein only when phosphorylated at Ser608.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser608 of human Rb protein.
Background: The retinoblastoma tumor suppressor protein Rb regulates cell proliferation by controlling progression through the restriction point within the G1-phase of the cell cycle (1). Rb has three functionally distinct binding domains and interacts with critical
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23396365?dopt=Abstract
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