Product Name: Phospho-Rb (Ser608) Antibody#2181
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1265917-14-3
Product: S1RA (hydrochloride)
Specificity Sensitivity: Phospho-Rb (Ser608) Antibody detects endogenous levels of Rb only when phosphorylated at serine 608.
Species Reactivity: Human, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser608 of human Rb. Antibodies are purified by protein A and peptide affinity chromatography.
Background: The retinoblastoma tumor suppressor protein Rb regulates cell proliferation by controlling progression through the restriction point within the G1-phase of the cell cycle (1). Rb has three functionally distinct binding domains and interacts with critical
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26621033?dopt=Abstract
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