Product Name: Phospho-RIP2 (Ser176) (E1I9J) Rabbit mAb#14397
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 59-87-0
Product: Nitrofurazone
Specificity Sensitivity: Phospho-RIP2 (Ser176) (E1I9J) Rabbit mAb recognizes endogenous levels of RIP2 protein only when phosphorylated at Ser176. This antibody also cross-reacts with unidentified proteins of approximately 25 kDa and 38 kDa in some cell lines.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser176 of human RIP2 protein.
Background: Receptor Interacting Protein 2 (RIP2) is a serine/threonine kinase with a carboxy-terminal caspase activation and recruitment domain (CARD). Association of RIP2 with the tumor necrosis factor receptor (TNFR) causes activation of NF-κB and induction of apo
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22539981?dopt=Abstract
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