Product Name: Phospho-PLCγ2 (Tyr1217) Antibody#3871
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 3963-95-9
Product: Methacycline (hydrochloride)
Specificity Sensitivity: Phospho-PLCgamma2 (Tyr1217) Antibody detects endogenous levels of PLCgamma2 phosphorylated at tyrosine 1217. This antibody does not cross-react with phosphorylated PLCgamma1.
Species Reactivity: Human, Mouse
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1217 of human PLCgamma2. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Phosphoinositide-specific phospholipase C (PLC) plays a significant role in transmembrane signaling. In response to extracellular stimuli such as hormones, growth factors and neurotransmitters, PLC hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) t
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19996106?dopt=Abstract
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