Product Name: Phospho-PLCγ1 (Ser1248) (D25A9) Rabbit mAb#8713
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry: 1:200
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 24169-02-6
Product: Econazole (nitrate)
Specificity Sensitivity: Phospho-PLCγ1 (Ser1248) (D25A9) Rabbit mAb recognizes endogenous levels of PLCγ1 protein only when phosphorylated at Ser1248.
Species Reactivity: Human, Mouse, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser1248 of human PLCγ1 protein.
Background: Phosphoinositide-specific phospholipase C (PLC) plays a significant role in transmembrane signaling. In response to extracellular stimuli such as hormones, growth factors, and neurotransmitters, PLC hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2)
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24163244?dopt=Abstract
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