Product Name: Phospho-M-CSF Receptor (Tyr699) (D10B11) Rabbit mAb#12251
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1014-70-6
Product: Simetryn
Specificity Sensitivity: Phospho-M-CSF Receptor (Tyr699) (D10B11) Rabbit mAb detects endogenous levels of M-CSF receptor only when phosphorylated at Tyr699. This antibody may cross-react with other activated tyrosine kinases including PDGF receptors and EGFR.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr699 of human M-CSF Receptor protein.
Background: Macrophage-colony stimulating factor (M-CSF, CSF-1) receptor is an integral membrane tyrosine kinase encoded by the c-fms proto-oncogene. M-CSF receptor is expressed in monocytes (macrophages and their progenitors) and drives growth and development of thi
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26924290?dopt=Abstract
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