Product Name: Phospho-HER2/ErbB2 (Tyr1248)/EGFR (Tyr1173) Antibody#2244
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1333146-24-9
Product: ILK-IN-1
Specificity Sensitivity: Phospho-HER2/ErbB2 (Tyr1248)/ EGFR (Tyr 1173) Antibody detects ErbB2 only when phosphorylated at tyrosine 1248 and EGFR only when phosphorylated at tyrosine 1173.
Species Reactivity: Human, Mouse
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1248 of human ErbB2. Antibodies are purified by protein A and peptide affinity chromatography.
Background: The ErbB2 (HER2) proto-oncogene encodes a 185 kDa transmembrane, receptor-like glycoprotein with intrinsic tyrosine kinase activity (1). While ErbB2 lacks an identified ligand, ErbB2 kinase activity can be activated in the absence of a ligand when overexp
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25190801?dopt=Abstract
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