Product Name: Phospho-EGF Receptor (Tyr998) (C24A5) Rabbit mAb#2641
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1004990-28-6
Product: AKT inhibitor
Specificity Sensitivity: Phospho-EGF Receptor (Tyr998) (C24A5) Rabbit mAb detects endogenous levels of EGF receptor only when phosphorylated at Tyr998. This antibody may weakly cross-react with other tyrosine-phosphorylated proteins.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr998 of human EGF receptor.
Background: The epidermal growth factor (EGF) receptor is a transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling, internalization, and lysos
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20209123?dopt=Abstract
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