Product Name: Phospho-EGF Receptor (Tyr845) (D63B4) Rabbit mAb#6963
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 593274-97-6
Product: Integrin Antagonists 27
Specificity Sensitivity: Phospho-EGF Receptor (Tyr845) (D63B4) Rabbit mAb recognizes endogenous levels of EGFR protein only when phosphorylated at Tyr845. This antibody may detect other activated ErbB family members.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr845 of human EGFR protein.
Background: The epidermal growth factor (EGF) receptor is a transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling, internalization, and lysos
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24582552?dopt=Abstract
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