Product Name: Phospho-DARPP-32 (Thr34) (D27A4) Rabbit mAb#12438
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1402821-24-2
Product: Ca2+ channel agonist 1
Specificity Sensitivity: Phospho-DARPP-32 (Thr34) (D27A4) Rabbit mAb detects endogenous levels of DARPP-32 only when phosphorylated at Thr34.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr34 of human DARPP-32 protein.
Background: DARPP-32 (dopamine and cyclic AMP-regulated phosphoprotein, relative molecular mass 32,000) is a cytosolic protein highly enriched in medium-sized spiny neurons of the neostriatum (1). It is a bifunctional signaling molecule that controls serine/threonine
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21734270?dopt=Abstract
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