Product Name: Phospho-CD79A (Tyr182) (D1B9) Rabbit mAb#14732
Application: Dilutions
Western Blotting:
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 349085-82-1
Product: GSK137647A
Specificity Sensitivity: Phospho-CD79A (Tyr182) Rabbit mAb recognizes endogenous levels of human CD79A protein only when phosphorylated on Tyr188. This corresponds to Tyr182 of mouse CD79A protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr188 of human CD79A protein. The phosphopeptide sequence is identical to the region surrounding Tyr182 of mouse CD79A protein.
Background: Antigen receptors found on the surface of B cells contain a heterodimeric signaling component composed of CD79A and CD79B, also known as Ig α and Ig β, respectively (1,2). Presence of this receptor complex is essential for B-cell development and function
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27510977?dopt=Abstract
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