Product Name: Phospho-Beclin-1 (Ser93) (D9A5G) Rabbit mAb#14717
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 193149-74-5
Product: WST-8
Specificity Sensitivity: Phospho-Beclin-1 (Ser93) (D9A5G) Rabbit mAb recognizes endogenous levels of Beclin-1 protein only when phosphorylated at Ser93. This antibody recognizes single phosphorylation of Ser93 to a greater extent than dual phosphorylation at Ser93 and Ser96. This
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser93 of human Beclin-1 protein (Ser91 in mouse).
Background: Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of proteins activated in response to nutrient deprivation and in neurodegenerative conditions (1). One of the proteins critical to this process is Beclin-1, the mammalian orthol
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21414768?dopt=Abstract
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