Product Name: PSMD10/Gankyrin Antibody#12985
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 122-11-2
Product: Sulfadimethoxine
Specificity Sensitivity: PSMD10/Gankyrin Antibody recognizes endogenous levels of total PSMD10/Gankyrin protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human PSMD10/Gankyrin protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: PSMD10/Gankyrin is an ankyrin-repeat chaperone protein that is involved in the assembly of the 19S regulatory particle of the proteasome (1). Reasearch studies have demonstrated that PSMD10 is oncogenic and is overexpressed in hepatocullar carcinomas (2).
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25267789?dopt=Abstract
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