Product Name: Human TNF-α Neutralizing (D1B4) Rabbit mAb#7321
Application: Dilutions
Western Blotting:
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Store lyophilized material at -20ºC. After reconstitution, recommended storage at 4ºC for 1 month or -20ºC for 6 months. Avoid repeated freeze/thawing.
CAS NO.: 116686-15-8
Product: FK 3311
Specificity Sensitivity: Human TNF-α Neutralizing (D1B4) Rabbit mAb binds to human TNF-α and neutralizes its cytotoxic effects. This antibody does not cross-react with mouse TNF-α.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a recombinant human TNF-α protein.
Background: TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein (1,2). Membrane-bound TNF-α is cleaved by the metalloprotease TACE/ADAM17 to generate a soluble homotrimer (2). Both membrane and soluble forms of TN
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24810053?dopt=Abstract
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