Product Name: EGF Receptor (E746-A750del Specific) (D6B6) XP® Rabbit mAb#2085
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry: 1:100
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 305834-79-1
Product: SC79
Specificity Sensitivity: EGF Receptor (E746-A750del Specific) (D6B6) XP® Rabbit mAb detects endogenous levels of EGFR E746-A750del mutant protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to E746-A750del mutant sequence of human EGFR.
Background: The epidermal growth factor (EGF) receptor is a 170 kDa transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Research studies have shown that somatic mutations in the tyrosine kinase domain of EGF receptor (EGFR) are present in a sub
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21084118?dopt=Abstract
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