Product Name: Dvl2 Antibody#3216
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:200
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 51298-62-5
Product: L-NAME (hydrochloride)
Specificity Sensitivity: Dvl2 Antibody detects endogenous levels of total Dvl2 protein. It does not cross-react with Dvl3.
Species Reactivity: Human, Mouse, Rat, Hamster, Monkey, Mink
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser638 of human Dvl2. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Dishevelled (Dsh) proteins are important intermediates of Wnt signaling pathways. Dsh inhibits glycogen synthase kinase-3β promoting β-catenin stabilization. Dsh proteins also participate in the planar cell polarity pathway by acting through JNK (1,2). Th
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23777308?dopt=Abstract
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