Product Name: DNMT1 (D63A6) XP® Rabbit mAb#5032
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 749269-83-8
Product: CHF5074
Specificity Sensitivity: DNMT1 (D63A6) XP® Rabbit mAb detects endogenous levels of total DNMT1 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the sequence of human DNMT1 protein.
Background: Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development (1,2). Three families of mammalian DNA methyltransferases have
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26162681?dopt=Abstract
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