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Product Name: DNA-PKcs Antibody#4602
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 20324-87-2
Product: AMI-1
Specificity Sensitivity: DNA-PKcs Antibody detects endogenous levels of DNA-PKcs protein.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to amino acids near the carboxy-terminus of human DNA-PKcs. Antibodies are purified by protein A and peptide affinity chromatography.
Background: DNA-dependent protein kinase (DNA-PK) is an important factor in the repair of double-stranded breaks in DNA. Cells lacking DNA-PK or in which DNA-PK is inhibited fail to show proper nonhomologous end-joining (NHEJ) (1-7). DNA-PK is composed of two DNA-bin
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27631877?dopt=Abstract

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Author: Interleukin Related