Product Name: DNA-PKcs (3H6) Mouse mAb#12311
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry: 1:50
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 193620-69-8
Product: TAS-301
Specificity Sensitivity: DNA-PKcs (3H6) Mouse mAb recognizes endogenous levels of total DNA-PKcs protein.
Species Reactivity: Human, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a recombinant protein fragment specific to human DNA-PKcs protein expressed in E.coli.
Background: DNA-dependent protein kinase (DNA-PK) is an important factor in the repair of double-stranded breaks in DNA. Cells lacking DNA-PK or in which DNA-PK is inhibited fail to show proper nonhomologous end-joining (NHEJ) (1-7). DNA-PK is composed of two DNA-bin
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27942222?dopt=Abstract
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