Product Name: DJ-1 (D21E11) Rabbit mAb#5560
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1303607-60-4
Product: SAR405838
Specificity Sensitivity: DJ-1 (D21E11) Rabbit mAb detects endogenous levels of total DJ-1 protein. DJ-1 (D21E11) Rabbit mAb is recommended to detect human samples but may also detect mouse and rat samples weakly.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly150 of human DJ-1 protein.
Background: Parkinsons disease (PD) is characterized by the presence of Lewy bodies (intracellular inclusions) and by the loss of dopaminergic neurons. Research studies have shown that mutations in α-synuclein, Parkin, and DJ-1 are linked to PD (1). α-synuclein is a
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18973746?dopt=Abstract
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