Product Name: DFF45/DFF35 Antibody#9732
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 94424-50-7
Product: Quinagolide (hydrochloride)
Specificity Sensitivity: DFF45/DFF35 Antibody detects endogenous levels of total full length DFF45 and/or full length DFF35. The antibody does not cross-react with related proteins.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp224 of human DFF45. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Human DFF45 and its mouse homologue ICAD function in normal cells as chaperones for caspase-activated deoxyribonuclease (DFF40 or CAD) during its synthesis (1). The association of DFF45 (or its isoform DFF35) with DFF40 inhibits the DNAse activity of the
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25722947?dopt=Abstract
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